The LC8-RavP ensemble structure evinces a role for LC8 in regulating Lyssavirus polymerase functionality

The rabies and Ebola viruses recruit the highly conserved host protein LC8 for their own reproductive success. In vivo knockouts of the LC8 recognition motif within the rabies virus phosphoprotein (RavP) result in completely non-lethal viral infections. In this work, we examine the molecular role LC...

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Detaylı Bibliyografya
Yayımlandı:J Mol Biol
Asıl Yazarlar: Jespersen, Nathan E., Leyrat, Cedric, Gérard, Francine C., Bourhis, Jean-Marie, Blondel, Danielle, Jamin, Marc, Barbar, Elisar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060403/
https://ncbi.nlm.nih.gov/pubmed/31634467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.10.011
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