Loss of Estrogen Receptors is Associated with Increased Tumor Aggression in Laryngeal Squamous Cell Carcinoma

Laryngeal squamous cell carcinoma (LSCC) responds to 17β-estradiol via estrogen-receptor (ER, transcribed from ESR1) dependent mechanisms, but is not recognized as a hormonally responsive cancer. 17β-estradiol production by LSCC cell lines UM-SCC-11A and UM-SCC-12 was examined. Wild type (WT) and ES...

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Udgivet i:Sci Rep
Main Authors: Verma, Anjali, Schwartz, Nofrat, Cohen, David J., Patel, Vaidehi, Nageris, Benny, Bachar, Gideon, Boyan, Barbara. D., Schwartz, Zvi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060328/
https://ncbi.nlm.nih.gov/pubmed/32144339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60675-2
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