A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation

Pluripotent stem cell-derived cardiomyocytes (PSC-CMs) hold great promise for disease modeling and drug discovery. However, PSC-CMs exhibit immature phenotypes in culture, and the lack of maturity limits their broad applications. While physical and functional analyses are generally used to determine...

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Udgivet i:Sci Rep
Main Authors: Chanthra, Nawin, Abe, Tomoyuki, Miyamoto, Matthew, Sekiguchi, Kiyotoshi, Kwon, Chulan, Hanazono, Yutaka, Uosaki, Hideki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060274/
https://ncbi.nlm.nih.gov/pubmed/32144297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61163-3
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