Pathophysiological changes of the lower urinary tract behind voiding dysfunction in streptozotocin-induced long-term diabetic rats

We evaluated pathophysiological characteristics of the lower urinary tract dysfunction in a streptozotocin (STZ)-induced diabetic rat model. STZ (60 mg/kg) was injected intraperitoneally into male Wistar rats. In vitro bladder muscle strip experiments, in vivo cystometry, and simultaneous recordings...

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Published in:Sci Rep
Main Authors: Masuda, Kazuki, Aizawa, Naoki, Watanabe, Daiji, Okegawa, Takatsugu, Kume, Haruki, Igawa, Yasuhiko, Fukuhara, Hiroshi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060249/
https://ncbi.nlm.nih.gov/pubmed/32144403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61106-y
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