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Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension

Cells in a tumor microenvironment are exposed to spatial and temporal variations in oxygen tension due to hyperproliferation and immature vascularization. Such spatiotemporal oxygen heterogeneity affects the behavior of cancer cells, leading to cancer growth and metastasis, and thus, it is essential...

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Detalhes bibliográficos
Publicado no:APL Bioeng
Main Authors: Koens, Rei, Tabata, Yugo, Serrano, Jean C., Aratake, Satoshi, Yoshino, Daisuke, Kamm, Roger D., Funamoto, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060087/
https://ncbi.nlm.nih.gov/pubmed/32161836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5127069
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