A Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions

Rosuvastatin, is a widely-used statin for the treatment of hypercholesterolemia and the prevention of cardiovascular diseases. Although rosuvastatin is well tolerated, about 3/10.000 patients can suffer severe myopathy. Rhabdomyolysis is a severe medical condition that causes injury to the skeletal...

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Dades bibliogràfiques
Publicat a:Pharmgenomics Pers Med
Autors principals: Calderon-Ospina, Carlos Alberto, Hernández-Sómerson, Mario, García, Ana María, Mejia, Adriana, Tamayo-Agudelo, Caroll, Laissue, Paul, Fonseca Mendoza, Dora Janeth
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Case Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060025/
https://ncbi.nlm.nih.gov/pubmed/32184647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S228709
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