Pheochromocytoma and Paraganglioma Patients With Poor Survival Often Show Brown Adipose Tissue Activation

CONTEXT: Pheochromocytomas/paragangliomas (PPGLs) are neuroendocrine tumors that can secrete norepinephrine (NE). Brown adipose tissue (BAT) activation is mediated through the action of NE on β-adrenoceptors (β-ARs). In some malignancies, BAT activation is associated with higher cancer activity. OBJ...

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Udgivet i:J Clin Endocrinol Metab
Main Authors: Abdul Sater, Zahraa, Jha, Abhishek, Hamimi, Ahmed, Mandl, Adel, Hartley, Iris R, Gubbi, Sriram, Patel, Mayank, Gonzales, Melissa, Taïeb, David, Civelek, Ali Cahid, Gharib, Ahmed M, Auh, Sungyoung, O’Mara, Alana E, Pacak, Karel, Cypess, Aaron M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Clinical Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059996/
https://ncbi.nlm.nih.gov/pubmed/31903484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz314
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