Reduced Insulin Clearance and Insulin-Degrading Enzyme Activity Contribute to Hyperinsulinemia in African Americans

BACKGROUND: African Americans (AAs) are at a higher risk for developing type 2 diabetes compared with non-Hispanic whites (NHWs). The causal role of β-cell glucose sensitivity (β-GS) and insulin clearance in hyperinsulinemia in AA adults is unclear. OBJECTIVE: Using a cross-sectional study design, w...

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Publicado en:J Clin Endocrinol Metab
Autores principales: Fosam, Andin, Sikder, Shanaz, Abel, Brent S, Tella, Sri Harsha, Walter, Mary F, Mari, Andrea, Muniyappa, Ranganath
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059993/
https://ncbi.nlm.nih.gov/pubmed/32052016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa070
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