Endocannabinoid modulating drugs improve anxiety but not the expression of conditioned fear in a rodent model of post-traumatic stress disorder

The endocannabinoid (eCB) system is a potential target for the treatment of symptoms of post-traumatic stress disorder (PTSD). Similar to clinical PTSD, approximately 25–30% of rats that undergo cued fear conditioning exhibit impaired extinction learning. In addition to extinction-resistant fear, th...

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Publicado no:Neuropharmacology
Main Authors: Vimalanathan, Akshayan, Gidyk, Darryl C., Diwan, Mustansir, Gouveia, Flavia V., Lipsman, Nir, Giacobbe, Peter, Nobrega, José N., Hamani, Clement
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059978/
https://ncbi.nlm.nih.gov/pubmed/31962287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.107965
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