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The pivotal role of micro-environmental cells in a human blood–brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis

BACKGROUND: The blood–brain barrier (BBB) is altered in several diseases of the central nervous system. For example, the breakdown of the BBB during cerebral ischemia in stroke or traumatic brain injury is a hallmark of the diseases’ progression. This functional damage is one key event which is atte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Fluids Barriers CNS
Hauptverfasser: Gerhartl, Anna, Pracser, Nadja, Vladetic, Alexandra, Hendrikx, Sabrina, Friedl, Heinz-Peter, Neuhaus, Winfried
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059670/
https://ncbi.nlm.nih.gov/pubmed/32138745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-020-00179-3
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