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A Pathogenic Missense Variant (c.1617G>A, p.Met539Ile) in UBA1 Causing Infantile X-Linked Spinal Muscular Atrophy (SMAX2)

Background: Infantile X-linked spinal muscular atrophy (SMAX2) is a rare type of spinal muscular atrophy associated with UBA1 variants. Methods: Clinical imaging and neurophysiological tests were performed on a Chinese patient with SMAX2. Further, focused panel sequencing of UBA1 was carried out on...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Wang, Xin Hua, Zhang, Lin Mei, Yang, Xue, Zhou, Shui Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059435/
https://ncbi.nlm.nih.gov/pubmed/32181232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2020.00064
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