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Mutation effect estimation on protein–protein interactions using deep contextualized representation learning
The functional impact of protein mutations is reflected on the alteration of conformation and thermodynamics of protein–protein interactions (PPIs). Quantifying the changes of two interacting proteins upon mutations is commonly carried out by computational approaches. Hence, extensive research effor...
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| Publicado no: | NAR Genom Bioinform |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7059401/ https://ncbi.nlm.nih.gov/pubmed/32166223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa015 |
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