Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice

BACKGROUND: Maternal smoking of traditional or electronic cigarettes during pregnancy, which constitutes developmental nicotine exposure (DNE), heightens the risk of neurodevelopmental disorders including ADHD, autism, and schizophrenia in children. Modeling the intergenerationally transmissible imp...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Buck, Jordan M., O’Neill, Heidi C., Stitzel, Jerry A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059320/
https://ncbi.nlm.nih.gov/pubmed/32138755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00332-0
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