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Heparinized chitosan stabilizes the bioactivity of BMP-2 and potentiates the osteogenic efficacy of demineralized bone matrix

BACKGROUND: Demineralized bone matrix (DBM), an allograft bone processed to better expose osteoinductive factors such as bone morphogenetic proteins (BMPs), is increasingly used for clinical bone repair. However, more extensive use of DBM is limited by its unpredictable osteoinductivity and low bone...

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Detalhes bibliográficos
Publicado no:J Biol Eng
Main Authors: Kim, Soyon, Fan, Jiabing, Lee, Chung-Sung, Chen, Chen, Bubukina, Ksenia, Lee, Min
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059291/
https://ncbi.nlm.nih.gov/pubmed/32165922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-020-0231-y
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