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Molecular Mechanisms of PALB2 Function and Its Role in Breast Cancer Management
Partner and localizer of BRCA2 (PALB2) is vital for homologous recombination (HR) repair in response to DNA double-strand breaks (DSBs). PALB2 functions as a tumor suppressor and participates in the maintenance of genome integrity. In this review, we summarize the current knowledge of the biological...
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| Pubblicato in: | Front Oncol |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7059202/ https://ncbi.nlm.nih.gov/pubmed/32185139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00301 |
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