Effect of Topiramate on Morphine-induced Conditioned Place Preference (CPP) in Rats: Role of ERK and CREB Proteins in Hippocampus and Cerebral Cortex

In this study, the effect of topiramate, as an antiepileptic drug, was evaluated on morphine craving in rats. The conditioned place preference (CPP) test was used for this purpose. Repeated administration of morphine (10 mg/kg, i.p. for 4 days) induced significant CPP. Administration of topiramate (...

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Detalhes bibliográficos
Publicado no:Iran J Pharm Res
Main Authors: Bagherpasand, Nima, Mehri, Soghra, Jafari Shahroudi, Mahdieh, Tabatabai, Seyed Meghdad, Khezri, Ali, Fathi, Mohammad, Abnous, Khalil, Imenshahidi, Mohsen, Hosseinzadeh, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059042/
https://ncbi.nlm.nih.gov/pubmed/32184865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.1100873
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