Effect of Topiramate on Morphine-induced Conditioned Place Preference (CPP) in Rats: Role of ERK and CREB Proteins in Hippocampus and Cerebral Cortex

In this study, the effect of topiramate, as an antiepileptic drug, was evaluated on morphine craving in rats. The conditioned place preference (CPP) test was used for this purpose. Repeated administration of morphine (10 mg/kg, i.p. for 4 days) induced significant CPP. Administration of topiramate (...

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Dettagli Bibliografici
Pubblicato in:Iran J Pharm Res
Autori principali: Bagherpasand, Nima, Mehri, Soghra, Jafari Shahroudi, Mahdieh, Tabatabai, Seyed Meghdad, Khezri, Ali, Fathi, Mohammad, Abnous, Khalil, Imenshahidi, Mohsen, Hosseinzadeh, Hossein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shaheed Beheshti University of Medical Sciences 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059042/
https://ncbi.nlm.nih.gov/pubmed/32184865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.1100873
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