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Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42

Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood. We found that the loss of Fak1a impaired epiboly, convergent extension and hypoblast cell...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Hung, I-Chen, Chen, Tsung-Ming, Lin, Jing-Ping, Tai, Yu-Ling, Shen, Tang-Long, Lee, Shyh-Jye
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058935/
https://ncbi.nlm.nih.gov/pubmed/32097584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190273
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