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A polygenic resilience score moderates the genetic risk for schizophrenia
Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531–538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseases, we posited the existence of genetic variants that promote resilience to highly heritable p...
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| Veröffentlicht in: | Mol Psychiatry |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7058518/ https://ncbi.nlm.nih.gov/pubmed/31492941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0463-8 |
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