Differentiation of human colon tissue in culture: Effects of calcium on trans-epithelial electrical resistance and tissue cohesive properties

BACKGROUND AND AIMS: Human colonoid cultures maintained under low-calcium (0.25 mM) conditions undergo differentiation spontaneously and, concomitantly, express a high level of tight junction proteins, but not desmosomal proteins. When calcium is included to a final concentration of 1.5–3.0 mM (prov...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: McClintock, Shannon D., Attili, Durga, Dame, Michael K., Richter, Aliah, Silvestri, Sabrina S., Berner, Maliha M., Bohm, Margaret S., Karpoff, Kateryna, McCarthy, Caroline L., Spence, Jason R., Varani, James, Aslam, Muhammad N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058309/
https://ncbi.nlm.nih.gov/pubmed/32134920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222058
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