Odontogenic infection by Porphyromonas gingivalis exacerbates fibrosis in NASH via hepatic stellate cell activation

Odontogenic infection of Porphyromonas gingivalis (P.g.), a major periodontal pathogen, exacerbates pathological progression of non-alcoholic steatohepatitis (NASH). In this study, we aimed to clarify the detailed mechanism in which P.g. induced hepatic stellate cells (HSCs; key effector cells in li...

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Pubblicato in:Sci Rep
Autori principali: Nagasaki, Atsuhiro, Sakamoto, Shinnichi, Chea, Chanbora, Ishida, Eri, Furusho, Hisako, Fujii, Makiko, Takata, Takashi, Miyauchi, Mutsumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058079/
https://ncbi.nlm.nih.gov/pubmed/32139740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60904-8
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