Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients

Tumor-associated macrophages (TAMs) are frequently the most abundant immune cells in cancers and are associated with poor survival. Here, we generated TAM molecular signatures from K14cre;Cdh1(flox/flox);Trp53(flox/flox) (KEP) and MMTV-NeuT (NeuT) transgenic mice that resemble human invasive lobular...

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Foilsithe in:Cell Rep
Main Authors: Tuit, Sander, Salvagno, Camilla, Kapellos, Theodore S., Hau, Cheei-Sing, Seep, Lea, Oestreich, Marie, Klee, Kathrin, de Visser, Karin E., Ulas, Thomas, Schultze, Joachim L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cell Press 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057267/
https://ncbi.nlm.nih.gov/pubmed/31665635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.09.067
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