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Dual mechanisms of posttranscriptional regulation of Tet2 by Let-7 microRNA in macrophages
Tet methylcytosine dioxygenase 2 (Tet2) is an epigenetic regulator that removes methyl groups from deoxycytosine residues in DNA. Tet2-deficient murine macrophages show increased lipopolysaccharide (LPS)-induced and spontaneous inflammation at least partially because Tet2 acts to restrain interleuki...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7056939/ https://ncbi.nlm.nih.gov/pubmed/31160465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811040116 |
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