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The base pair-scale diffusion of nucleosomes modulates binding of transcription factors

The structure of promoter chromatin determines the ability of transcription factors (TFs) to bind to DNA and therefore has a profound effect on the expression levels of genes. However, the role of spontaneous nucleosome movements in this process is not fully understood. Here, we developed a single-m...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Rudnizky, Sergei, Khamis, Hadeel, Malik, Omri, Melamed, Philippa, Kaplan, Ariel
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056936/
https://ncbi.nlm.nih.gov/pubmed/31147470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815424116
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