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αvβ3 Integrin Antagonists Enhance Chemotherapy Response in an Orthotopic Pancreatic Cancer Model

Pancreatic cancer decreases survival time and quality of life because of drug resistance and peripheral neuropathy during conventional treatment. This study was undertaken to investigate whether αvβ3 integrin receptor antagonist compounds NDAT and XT199 can suppress the development of cisplatin resi...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Debreli Coskun, Melis, Sudha, Thangirala, Bharali, Dhruba J., Celikler, Serap, Davis, Paul J., Mousa, Shaker A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056702/
https://ncbi.nlm.nih.gov/pubmed/32174830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00095
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