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MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy

Although photodynamic therapy (PDT) has been clinically applied tumor hypoxia still greatly restricts the performance of this oxygen-dependent oncological treatment. The delivery of oxygen donors to tumor may produce excessive reactive oxygen species (ROS) and damage the peripheral tissues. Herein,...

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Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Zhao, Lingzhi, Li, Junyao, Su, Yaoquan, Yang, Liqiang, Chen, Liu, Qiang, Lei, Wang, Yajing, Xiang, Huijing, Tham, Huijun Phoebe, Peng, Juanjuan, Zhao, Yanli
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056313/
https://ncbi.nlm.nih.gov/pubmed/32181355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz0575
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