High-activity Classical and Alternative Complement Pathway Genotypes—Association With Donor-specific Antibody-triggered Injury and Renal Allograft Survival

BACKGROUND. Complement may contribute to donor-specific antibody (DSA)-triggered transplant injury. Here, we investigated whether the intrinsic strength of classical pathway and alternative pathway (AP) relates to the pathogenicity of DSA. METHODS. Classical pathway and AP high-activity genotypes we...

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Detalhes bibliográficos
Publicado no:Transplant Direct
Main Authors: Mező, Blanka, Reindl-Schwaighofer, Roman, Eskandary, Farsad, Heinzel, Andreas, Wahrmann, Markus, Doberer, Konstantin, Heilos, Andreas, Bond, Gregor, Kläger, Johannes, Kozakowski, Nicolas, Haslacher, Helmuth, Oberbauer, Rainer, Viklický, Ondřej, Hrubá, Petra, Halloran, Philip F., Rusai, Krisztina, Prohászka, Zoltán, Böhmig, Georg A.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2020
Assuntos:
Kidney Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056277/
https://ncbi.nlm.nih.gov/pubmed/32195325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000978
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