Metastatic Melanoma Patient Had a Complete Response with Clonal Expansion after Whole Brain Radiation and PD-1 Blockade

We report here on a patient with metastatic melanoma who had extensive brain metastases. After being treated with the sequential combination of whole brain radiation therapy followed by the PD-1–inhibitory antibody, pembrolizumab, the patient had a durable complete response. Retrospective laboratory...

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Библиографические подробности
Опубликовано в: :Cancer Immunol Res
Главные авторы: Haymaker, Cara L., Kim, DaeWon, Uemura, Marc, Vence, Luis M., Phillip, Ann, McQuail, Natalie, Brown, Paul D., Fernandez, Irina, Hudgens, Courtney W., Creasy, Caitlin, Hwu, Wen-Jen, Sharma, Padmanee, Tetzlaff, Michael T., Allison, James P., Hwu, Patrick, Bernatchez, Chantale, Diab, Adi
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055516/
https://ncbi.nlm.nih.gov/pubmed/28062513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0223
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