Modulation of nanoparticle uptake, intracellular distribution, and retention with docetaxel to enhance radiotherapy

OBJECTIVE: One of the major issues in current radiotherapy (RT) is the normal tissue toxicity. A smart combination of agents within the tumor would allow lowering the RT dose required while minimizing the damage to healthy tissue surrounding the tumor. We chose gold nanoparticles (GNPs) and docetaxe...

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Vydáno v:Br J Radiol
Hlavní autoři: Bannister, Aaron Henry, Bromma, Kyle, Sung, Wonmo, Monica, Mesa, Cicon, Leah, Howard, Perry, Chow, Robert L, Schuemann, Jan, Chithrani, Devika Basnagge
Médium: Artigo
Jazyk:Inglês
Vydáno: The British Institute of Radiology. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055427/
https://ncbi.nlm.nih.gov/pubmed/31778316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20190742
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