Effect of osmolytes on in-vitro aggregation properties of peptides derived from TGFBIp

Protein aggregation has been one of the leading triggers of various disease conditions, such as Alzheimer’s, Parkinson’s and other amyloidosis. TGFBI-associated corneal dystrophies are protein aggregation disorders in which the mutant TGFBIp aggregates and accumulates in the cornea, leading to a red...

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Vydáno v:Sci Rep
Hlavní autoři: Venkatraman, Anandalakshmi, Murugan, Elavazhagan, Lin, Shu Jun, Peh, Gary Swee Lim, Rajamani, Lakshminarayanan, Mehta, Jodhbir S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055237/
https://ncbi.nlm.nih.gov/pubmed/32132634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60944-0
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