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Non-CpG methylation biases bisulphite PCR towards low or unmethylated mitochondrial DNA: recommendations for the field

Mitochondrial DNA (mtDNA) is a circular genome of 16 kb that is present in multiple copies in mitochondria. mtDNA codes for genes that contribute to mitochondrial structure and function. A long-standing question has asked whether mtDNA is epigenetically regulated similarly to the nuclear genome. Rec...

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Vydáno v:Environ Epigenet
Hlavní autoři: Morris, Margaret J, Hesson, Luke B, Youngson, Neil A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055202/
https://ncbi.nlm.nih.gov/pubmed/32154030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eep/dvaa001
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