Priming with inflammatory cytokines is not a prerequisite to increase immune-suppressive effects and responsiveness of equine amniotic mesenchymal stromal cells

BACKGROUND: Equine amniotic mesenchymal stromal cells (AMSCs) and their conditioned medium (CM) were evaluated for their ability to inhibit in vitro proliferation of peripheral blood mononuclear cells (PBMCs) with and without priming. Additionally, AMSC immunogenicity was assessed by expression of M...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Lange-Consiglio, Anna, Romele, Pietro, Magatti, Marta, Silini, Antonietta, Idda, Antonella, Martino, Nicola Antonio, Cremonesi, Fausto, Parolini, Ornella
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055152/
https://ncbi.nlm.nih.gov/pubmed/32131892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01611-z
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