Prevention of multiple system atrophy using human bone marrow-derived mesenchymal stem cells by reducing polyamine and cholesterol-induced neural damages

BACKGROUND: Multiple system atrophy (MSA) is a sporadic neurodegenerative disorder of unknown etiology, but is closely associated with damage to dopaminergic neurons. MSA progression is rapid. Hence, long-term drug treatments do not have any therapeutic benefits. We assessed the inhibitory effect of...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Park, Kyung-Ran, Hwang, Chul Ju, Yun, Hyung-Mun, Yeo, In Jun, Choi, Dong-Young, Park, Pil-Hoon, Kim, Hyung Sook, Lee, Jung Tae, Jung, Young Suk, Han, Sang-Bae, Hong, Jin Tae
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055099/
https://ncbi.nlm.nih.gov/pubmed/32127052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01590-1
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