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Variants of uncertain significance in the era of high-throughput genome sequencing: a lesson from breast and ovary cancers

The promising expectations about personalized medicine have opened the path to routine large-scale sequencing and increased the importance of genetic counseling for hereditary cancers, among which hereditary breast and ovary cancers (HBOC) have a major impact. High-throughput sequencing, or Next-Gen...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Federici, Giulia, Soddu, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055088/
https://ncbi.nlm.nih.gov/pubmed/32127026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01554-6
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