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TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy

Cellular adaptation in response to nutrient limitation requires the induction of autophagy and lysosome biogenesis for the efficient recycling of macromolecules. Here, we discovered that starvation and TORC1 inactivation not only lead to the up-regulation of autophagy and vacuole proteins involved i...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Yang, Xi, Zhang, Weichao, Wen, Xin, Bulinski, Patrick J., Chomchai, Dominic A., Arines, Felichi Mae, Liu, Yun-Yu, Sprenger, Simon, Teis, David, Klionsky, Daniel J., Li, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055007/
https://ncbi.nlm.nih.gov/pubmed/32045480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902127
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