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Differential turnover of Nup188 controls its levels at centrosomes and role in centriole duplication
NUP188 encodes a scaffold component of the nuclear pore complex (NPC) and has been implicated as a congenital heart disease gene through an ill-defined function at centrioles. Here, we explore the mechanisms that physically and functionally segregate Nup188 between the pericentriolar material (PCM)...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7055002/ https://ncbi.nlm.nih.gov/pubmed/32211895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201906031 |
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