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Nek2 kinase displaces distal appendages from the mother centriole prior to mitosis

Distal appendages (DAs) of the mother centriole are essential for the initial steps of ciliogenesis in G1/G0 phase of the cell cycle. DAs are released from centrosomes in mitosis by an undefined mechanism. Here, we show that specific DAs lose their centrosomal localization at the G2/M transition in...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Viol, Linda, Hata, Shoji, Pastor-Peidro, Ana, Neuner, Annett, Murke, Florian, Wuchter, Patrick, Ho, Anthony D., Giebel, Bernd, Pereira, Gislene
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055001/
https://ncbi.nlm.nih.gov/pubmed/32211891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907136
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