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ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes

The intraluminal vesicles (ILVs) of endosomes mediate the delivery of activated signaling receptors and other proteins to lysosomes for degradation, but they also modulate intercellular communication when secreted as exosomes. The formation of ILVs requires four complexes, ESCRT-0, -I, -II, and -III...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Larios, Jorge, Mercier, Vincent, Roux, Aurélien, Gruenberg, Jean
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054990/
https://ncbi.nlm.nih.gov/pubmed/32049272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904113
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