Hypoxia differently modulates the release of mitochondrial and nuclear DNA

BACKGROUND: We investigated the influence of hypoxia on the concentration of mitochondrial and nuclear cell-free DNA (McfDNA and NcfDNA, respectively). METHOD: By an ultra-sensitive quantitative PCR-based assay, McfDNA and NcfDNA were measured in the supernatants of different colorectal cell lines,...

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Gepubliceerd in:Br J Cancer
Hoofdauteurs: Otandault, Amaelle, Abraham, Jean-Daniel, Al Amir Dache, Zahra, Khalyfa, Abdelnaby, Jariel-Encontre, Isabelle, Forné, Thierry, Prévostel, Corinne, Chouaib, Salem, Gozal, David, Thierry, Alain R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054557/
https://ncbi.nlm.nih.gov/pubmed/31929518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0716-y
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