Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy

BACKGROUND: Predictive preclinical models play an important role in the assessment of new treatment strategies and as avatar models for personalised medicine; however, reliable and timely model generation is challenging. We investigated the feasibility of establishing patient-derived xenograft (PDX)...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Kamili, Alvin, Gifford, Andrew J., Li, Nancy, Mayoh, Chelsea, Chow, Shu-Oi, Failes, Timothy W., Eden, Georgina L., Cadiz, Roxanne, Xie, Jinhan, Lukeis, Robyn E., Norris, Murray D., Haber, Michelle, McCowage, Geoffrey B., Arndt, Greg M., Trahair, Toby N., Fletcher, Jamie I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054410/
https://ncbi.nlm.nih.gov/pubmed/31919402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0682-4
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