Excessive Promoters as Silencers of Genes Horizontally Acquired by Escherichia coli

Horizontally acquired genes are usually transcriptionally inactive, although most of them are associated with genomic loci enriched with promoter-like sequences forming “promoter islands.” We hypothesized that lateral DNA transfer induces local mutagenesis, accumulating AT base pairs and creating pr...

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Veröffentlicht in:Front Mol Biosci
Hauptverfasser: Bykov, Aleksandr, Glazunova, Olga, Alikina, Olga, Sukharicheva, Natalia, Masulis, Irina, Shavkunov, Konstantin, Ozoline, Olga
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Molecular Biosciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054387/
https://ncbi.nlm.nih.gov/pubmed/32175329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00028
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