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Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data

Chromatin interaction studies can reveal how the genome is organized into spatially confined sub-compartments in the nucleus. However, accurately identifying sub-compartments from chromatin interaction data remains a challenge in computational biology. Here, we present Sub-Compartment Identifier (SC...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ashoor, Haitham, Chen, Xiaowen, Rosikiewicz, Wojciech, Wang, Jiahui, Cheng, Albert, Wang, Ping, Ruan, Yijun, Li, Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054322/
https://ncbi.nlm.nih.gov/pubmed/32127534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14974-x
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