CTLA-4 blockade boosts the expansion of tumor-reactive CD8(+) tumor-infiltrating lymphocytes in ovarian cancer

Adoptive cell therapy (ACT) with autologous tumor-infiltrating lymphocytes (TILs) can induce durable complete tumor regression in patients with advanced melanoma. Efforts are currently underway to expand this treatment modality to other cancer types. In the microenvironment of ovarian cancer, the en...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Friese, Christina, Harbst, Katja, Borch, Troels Holz, Westergaard, Marie Christine Wulff, Pedersen, Magnus, Kverneland, Anders, Jönsson, Göran, Donia, Marco, Svane, Inge Marie, Met, Özcan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054305/
https://ncbi.nlm.nih.gov/pubmed/32127601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60738-4
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