Older breast cancer survivors may harbor hereditary cancer predisposition pathogenic variants and are at risk for clonal hematopoiesis.

OBJECTIVE: Our goal was to identify pathogenic variants (PV) associated with germline cancer predisposition in an unselected cohort of older breast cancer survivors. Older patients with cancer may also be at higher risk for clonal hematopoiesis (CH) due to their age and chemotherapy exposure. Theref...

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Veröffentlicht in:J Geriatr Oncol
Hauptverfasser: Slavin, Thomas P., Sun, Can-Lan, Chavarri-Guerra, Yanin, Sedrak, Mina S., Katheria, Vani, Castillo, Danielle, Herzog, Josef, Dale, William, Hurria, Arti, Weitzel, Jeffrey N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054130/
https://ncbi.nlm.nih.gov/pubmed/31575519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgo.2019.09.004
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