Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1-related anti-apoptotic proteins

Cholangiocarcinoma (CCA) is a cancer of biliary epithelium. Late diagnosis and resistance to conventional chemotherapy are the major obstacles in CCA treatment. Increased expression of anti-apoptotic proteins are observed in CCA, which might confer chemoresistance. Thus, modulations of anti-apoptoti...

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Vydáno v:Int J Mol Med
Hlavní autoři: Saranaruk, Paksiree, Kariya, Ryusho, Sittithumcharee, Gunya, Boueroy, Parichart, Boonmars, Thidarut, Sawanyawisuth, Kanlayanee, Wongkham, Chaisiri, Wongkham, Sopit, Okada, Seiji, Vaeteewoottacharn, Kulthida
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053871/
https://ncbi.nlm.nih.gov/pubmed/32124934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4482
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