Hesperetin reverses P-glycoprotein-mediated cisplatin resistance in DDP-resistant human lung cancer cells via modulation of the nuclear factor-κB signaling pathway

Lung cancer is the leading cause of cancer-associated mortality worldwide. Cisplatin (DDP) is a first-line chemotherapeutic drug for the treatment of lung cancer; however, the majority of patients develop resistance to DDP. P-glycoprotein (P-gp), also referred to as multidrug resistance (MDR) protei...

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Publicado no:Int J Mol Med
Main Authors: Kong, Wencui, Ling, Xiaoming, Chen, Ying, Wu, Xiaoli, Zhao, Zhongquan, Wang, Wenwu, Wang, Shuiliang, Lai, Guoxiang, Yu, Zongyang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053858/
https://ncbi.nlm.nih.gov/pubmed/32124932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4485
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