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Model systems for studying the assembly, trafficking, and secretion of apoB lipoproteins using fluorescent fusion proteins

apoB exists as apoB100 and apoB48, which are mainly found in hepatic VLDLs and intestinal chylomicrons, respectively. Elevated plasma levels of apoB-containing lipoproteins (Blps) contribute to coronary artery disease, diabetes, and other cardiometabolic conditions. Studying the mechanisms that driv...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Walsh, Meghan T., Celestin, Oni M., Thierer, James H., Rajan, Sujith, Farber, Steven A., Hussain, M. Mahmood
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053841/
https://ncbi.nlm.nih.gov/pubmed/31888978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000259
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