A wake-active locomotion circuit depolarizes a sleep-active neuron to switch on sleep

Sleep-active neurons depolarize during sleep to suppress wakefulness circuits. Wake-active wake-promoting neurons in turn shut down sleep-active neurons, thus forming a bipartite flip-flop switch. However, how sleep is switched on is unclear because it is not known how wakefulness is translated into...

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Publicado en:PLoS Biol
Autores principales: Maluck, Elisabeth, Busack, Inka, Besseling, Judith, Masurat, Florentin, Turek, Michal, Busch, Karl Emanuel, Bringmann, Henrik
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053779/
https://ncbi.nlm.nih.gov/pubmed/32078631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000361
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