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Diversification of polyketide structures via synthase engineering
Polyketide natural products possess diverse biological activities including antibiotic, anticancer, and immunosuppressive. Their equally varied and complex structures arise from head-to-tail condensation of simple carboxyacyl monomers. Since the seminal discovery that biosynthesis of polyketides suc...
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| Published in: | Medchemcomm |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Royal Society of Chemistry
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053703/ https://ncbi.nlm.nih.gov/pubmed/32180918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00141g |
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