Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR

Background: It is generally thought that the occurrence and progression of osteoarthritis (OA) results from multiple causes, including degradation and destruction of the cartilage matrix and aging of chondrocytes. Metformin is a first-line drug for the treatment of diabetes, and has great potential...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Feng, Xiaofeng, Pan, Jianying, Li, Junyan, Zeng, Chun, Qi, Weizhong, Shao, Yan, Liu, Xin, Liu, Liangliang, Xiao, Guozhi, Zhang, Haiyan, Bai, Xiaochun, Cai, Daozhang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053618/
https://ncbi.nlm.nih.gov/pubmed/31945013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102635
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