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K63 ubiquitin chains target NLRP3 inflammasome for autophagic degradation in ox-LDL-stimulated THP-1 macrophages

Inflammation, especially involving the NLRP3 inflammasome, is critical to atherosclerotic plaque formation. Enhanced autophagy can inhibit the development of atherosclerosis, and recent studies have revealed that NLRP3 inflammasome can be degraded by autophagy in atherosclerosis. In the present stud...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhou, Zhenfeng, Zhu, Xiaoyan, Yin, Ruihua, Liu, Tianwei, Yang, Shaonan, Zhou, Lingyan, Pan, Xudong, Ma, Aijun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053591/
https://ncbi.nlm.nih.gov/pubmed/32003754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102710
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